Benchmarking the Role of Lipid Nanoparticles in Enhancing the Effectiveness of mRNA-Based Therapeutics
Time: 1:00 pm
day: Pre-Conference Workshop Day
Details:
Recent advances in medicine have led to the development of mRNA-based therapeutics, which have shown promise in treating various diseases. However, the effectiveness of these therapeutics is limited by their inability to penetrate cell membranes. By using lipid nanoparticles, the effectiveness of mRNA-based therapeutics can be greatly enhanced. In fact, several studies have shown that lipid nanoparticles can improve the delivery and efficacy of mRNA-based therapeutics in vivo. Thus, it is clear that lipid nanoparticles play a crucial role in the development of effective mRNA-based therapeutics.
Join this session to discuss:
- The latest advances in improving the stability of LNP’s to increase safety and efficiency
- The latest advances in storage of LNP’s to increase safety and global accessibility
- The different approaches to screen ionizable lipids to reach a high and efficient endosomal escape and a low immunogenicity
- Why production of LNPs with specific size and PDI according to the regulatory requirement remains a big challenge in mRNA delivery
- The most recent research in screening lipids to achieve targeted delivery to different tissues
